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In the study of endometrial cancer (EC), we found that Brusatol sensitizes the cancer to progestins by inhibiting the NRF2-TET1-AKR1C1 pathway, which reduces AKR1C1 expression and decreases progesterone metabolism [110]

People with malabsorption, post-bariatric anatomy, or active inflammatory bowel disease can absorb nutrients through a vein that they cant absorb through their gut

doi: 10.1007/s12603-022-1757-0 158